Is Tylenol Safe During Pregnancy? Risk Factors, Not Causation Metabolism of acetaminophen (paracetamol) in plantstwo independent pathways result in the formation of a glutathione and a glucose conjugate Environmental Science and Pollution Research Springer Nature Link Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: The History of Acetaminophen Office for Science and Society McGill University Frontiers Phytic acid attenuates acetaminophen induced hepatotoxicity via modulating iron mediated oxidative stress and SIRT 1 expression in mice Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health